epitope mapping within an internal region of TMTC4 of human origin
Modification Notes
The tetratricopeptide repeat (TPR) motif is a degenerate, 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways. At the sequence level, there can be up to 16 tandem TPR repeats, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity. TMTC4 (transmembrane and tetratricopeptide repeat containing 4) is a 741 amino acid multi-pass membrane protein that contains 8 TPR repeats and is expressed as multiple alternatively spliced isoforms. The gene encoding TMTC4 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of TMTC4 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of TMTC4 of human origin
Tissue Specificity
epitope mapping within an internal region of TMTC4 of human origin
Western blot analysis of TMTC4 expression in mouse brain tissue extract.
Application Notes
recommended for detection of TMTC4 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.