recommended for detection of ZNF396 of human origin by WB, IP and ELISA
Modification Notes
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF396 (Zinc finger protein 396), also known as ZSCAN14 (Zinc finger and SCAN domain-containing protein 14), is a 335 amino acid nuclear protein that contains one SCAN box domain and three C2H2-type zinc fingers. There are three isoforms of ZNF that are produced as a result of alternative splicing events. Both isoform 1 and 2 act as DNA-dependent transcriptional repressors. ZNF396 is strongly expressed in liver, moderately expressed in skeletal muscle and weakly expressed in spleen, kidney, prostate and pancreas.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of ZNF396 of human origin by WB IP and ELISA
Tissue Specificity
recommended for detection of ZNF396 of human origin by WB, IP and ELISA