Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human placenta showing nulear and cytolasmic staining of decidual and trophoblastic cells at low magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human placenta showing nulear and cytolasmic staining of decidual and trophoblastic cells at high magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.Application
Western blot analysis of TDRD3 expression in non-transfected 293T: (A), human TDRD3 transfected 293T: (B) and Jurkat (C) whole cell lysates.Application
Western blot analysis of TDRD3 expression in HT-1080 whole cell lysate.Application
Western blot analysis of TDRD3 expression in Jurkat whole cell lysate.| Product Name | TDRD3 Antibody (C-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the C-terminus of TDRD3 of human origin |
| Modification Notes | TDRD3 (tudor domain containing 3) is a 651 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one UBA domain and one tudor domain. Expressed in lung, brain, heart, liver, placenta, kidney, pancreas and skeletal muscle, TDRD3 exists as a component of mRNA stress granules and is thought to play a role in the translation of target mRNAs, as well as in the assembly and disassembly of stress granules. Multiple isoforms of TDRD3 exist due to alternative splicing events. The gene encoding TDRD3 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of TDRD3 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the C-terminus of TDRD3 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the C-terminus of TDRD3 of human origin |
| Entrez Gene | 81550 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human placenta showing nulear and cytolasmic staining of decidual and trophoblastic cells at low magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human placenta showing nulear and cytolasmic staining of decidual and trophoblastic cells at high magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
Application
Western blot analysis of TDRD3 expression in non-transfected 293T: (A), human TDRD3 transfected 293T: (B) and Jurkat (C) whole cell lysates.
Application
Western blot analysis of TDRD3 expression in HT-1080 whole cell lysate.
Application
Western blot analysis of TDRD3 expression in Jurkat whole cell lysate.| Application Notes | recommended for detection of TDRD3 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
