| Product Name | CCPG1 Antibody (X-21) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of CCPG1 of human origin by WB, IP and ELISA |
| Modification Notes | CCPG1 (cell cycle progression 1), also known as CPR8, is a 757 amino acid single-pass type II membrane protein that acts as an assembly platform for Rho protein signaling complexes. Involved in cell cycle regulation, CCPG1 limits guanine nucleotide exchange activity of Dbs, a Rho-specific guanine nucleotide exchange factor, toward Rho A, which results in an inhibition of both its transcriptional activation ability and its transforming activity. Considered a novel scaffold protein, CCPG1 exists as four isoforms produced by alternative splicing events. The gene encoding CCPG1 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of CCPG1 of human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of CCPG1 of human origin by WB, IP and ELISA |
| Entrez Gene | 9236 |
|---|
| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
