recommended for detection of SNIP1 of human origin by WB, IP and ELISA
Modification Notes
Members of the transforming growth factor-beta (TGF-∫) superfamily play critical roles in controlling cell growth and differentiation. Effects of TGF-∫ family ligands are mediated by Smad proteins. The Smad nuclear interacting protein (SNIP1) contains a forkhead-associated (FHA) domain and acts as a nuclear inhibitor of CBP/p300. SNIP1 potently inhibits the activity of NF-kappa B, which binds the C/H1 domain of CBP/p300, by competing for the binding site. SNIP1 is also thought to induce expression of Cyclin D1 to promote cellular proliferation. SNIP1 is ubiquitously expressed with high expression in heart and skeletal muscle. 47916
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of SNIP1 of human origin by WB IP and ELISA
Tissue Specificity
recommended for detection of SNIP1 of human origin by WB, IP and ELISA