recommended for detection of SMPX of human origin by WB, IP and ELISA; also reactive with additional species, including canine
Modification Notes
SMPX (small muscle protein, X-linked), also known as SRMX, is an 86 amino acid protein that is preferentially expressed at high levels in heart and skeletal muscle where it is thought to play a role in muscle structure during growth, repair and adaptation. Defects in the gene encoding SMPX, which maps to human chromosome X, may play a role in the development of X-linked cardiac or muscle disorders. Chromosome X, one of the two human sex chromosomes, contains nearly 153 million base pairs and encodes over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination, as an X and a Y chromosome lead to normal male development, while two copies of an X chromosome lead to normal female development. There are a number of conditions related to an abnormal number and combination of sex chromosomes , some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of SMPX of human origin by WB IP and ELISA also reactive with additional species including canine
Tissue Specificity
recommended for detection of SMPX of human origin by WB, IP and ELISA; also reactive with additional species, including canine