epitope mapping within an internal region of Rab 36 of human origin
Modification Notes
The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies. Increasing data suggests an important role for Rab proteins in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab proteins are also an integral part of endocytic pathways. Rab 36 is a ubiquitously expressed member of the Rab family of proteins and localizes to the Golgi membrane where it is believed to participate in protein transport. The gene encoding Rab 36 localizes to a critical region of chromosome 22 that is often deleted or involved in translocations in malignant rhabdoid tumors (MRTs). This suggests that Rab 36 may play a role in the development of MRTs.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIFELISA
recommended for detection of Rab 36 of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine and bovine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of Rab 36 of human origin
Tissue Specificity
epitope mapping within an internal region of Rab 36 of human origin
recommended for detection of Rab 36 of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine and bovine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.