Application
Western blot analysis of GSC2 expression in Hep G2 whole cell lysate.Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney tissue showing nuclear localization.| Product Name | GSC2 Antibody (T-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of GSC2 of human origin by WB, IP, IF, IHC(P) and ELISA |
| Modification Notes | GSC2 (homeobox protein goosecoid-2), also known as GSCL (homeobox protein goosecoid-like), is a 205 amino acid nuclear protein that shares high homolgy to GSC, a protein involved in the development of the lower mandible and its associated musculature as well as components of the inner ear and the external auditory meatus. Since its expression pattern begins in early embryo, GSC2 may play an indirect role in the development of neural crest derived structures. Due to its chromosomal location and its role in early development, the gene encoding GSC2 is a major candidate for del22q11.2 (DiGeorge or velocardiofacial) syndrome, a disease characterized by craniofacial defects, thymic hypoplasia, cardiovascular anomalies, velopharyngeal insufficiency and skeletal muscle hypotonia. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of GSC2 of human origin by WB IP IF IHC(P) and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of GSC2 of human origin by WB, IP, IF, IHC(P) and ELISA |
| Entrez Gene | 2928 |
|---|
Application
Western blot analysis of GSC2 expression in Hep G2 whole cell lysate.
Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney tissue showing nuclear localization.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
