| Product Name | Liprin β2 Antibody (H-207) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 186-392 mapping within an internal region of Liprin β2 of human origin |
| Modification Notes | Liprins interact with members of the leukocyte common antigen-related (LAR) family of transmembrane protein tyrosine phosphatases, which are implicated in axon guidance and mammary gland development. Liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR phosphatases. Based on sequence similarites and binding characteristics, liprins are subdivided into å-type and ∫-type liprins. Both å- and ∫-liprins homodimerize via their N-terminal, coiled coil regions. Liprin ∫2 is expressed strongly in liver, kidney, intestine, heart, lung and testis, however it can be detected at low levels in brain and thymus. Four isoforms exist for Liprin ∫2 due to splicing variants. Isoform 1 respresents the full length protein. Isoform 2 lacks amino acids 459-469. Isoform 3 contains an alternative sequence for amino acids 127-200 and is truncated at amino acid 200. Isoform 4 lacks amino acids 459-469 and contains an alternative sequence for amino acids 877-882. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Liprin β2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 186-392 mapping within an internal region of Liprin &beta 2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 186-392 mapping within an internal region of Liprin β2 of human origin |
| Application Notes | recommended for detection of Liprin β2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
