| Product Name | LMF2 Antibody (P-17) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the N-terminus of LMF2 of human origin |
| Modification Notes | LMF2 (Lipase maturation factor 2), also known as TMEM112B (Transmembrane protein 112B) and TMEM153 (Transmembrane protein 153), is a 707 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum (ER) and belongs to the lipase maturation family. LMF2 is involved in the maturation of ER-localized proteins and is required for the transport of active LPL (lipoprotein lipase) through the secretory pathway. The gene encoding LMF2 maps to human chromosome 22, contains over 500 genes and about 49 million bases. Being the second smallest human chromosome, 22 contains a surprising variety of interesting genes. Phelan-McDermid syndrome, Neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. There are three isoforms of LMF2 that are expressed as a result of alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of LMF2 of human origin by WB, IF and ELISA also reactive with additional species, including bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of LMF2 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of LMF2 of human origin |
| Entrez Gene | 91289 |
|---|
| Application Notes | recommended for detection of LMF2 of human origin by WB, IF and ELISA also reactive with additional species, including bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
