epitope mapping within an extracellular domain of FLRT3 of human origin
Modification Notes
FLRT3 (fibronectin leucine rich transmembrane protein 3), also known as KIAA1469, is a 649 amino acid single-pass type I membrane protein that contains one fibronectin type-III domain and ten leucine-rich repeats and belongs to the fibronectin leucine rich transmembrane protein (FLRT) family. Expressed in heart, liver, lung, kidney, pancreas, brain, placenta and skeletal muscle, FLRT3 is thought to be involved in receptor signaling events and may play a role in both cell adhesion neurite outgrowth. Defects in the gene encoding mouse FLRT3 may lead to ventral closure, headfold fusion and endoderm migration defects, suggesting that FLRT3 is important for proper cell differentiation and development. FLRT3 exists as multiple alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 20.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of FLRT3 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with family members FLTR1 or FLTR2 also reactive with additional species, including equine, bovine, porcine and avian:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an extracellular domain of FLRT3 of human origin
Tissue Specificity
epitope mapping within an extracellular domain of FLRT3 of human origin
Western blot analysis of FLTR3 expression in non-transfected: (A) and human FLTR3 transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of FLRT3 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with family members FLTR1 or FLTR2 also reactive with additional species, including equine, bovine, porcine and avian:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.