Application
Western blot analysis of FOXE3 expression in non-transfected: (A) and human FOXE3 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of mouse recombinant FOXE3 fusion protein.| Product Name | FOXE3 Antibody (M-57) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 232-288 mapping at the C-terminus of FOXE3 of mouse origin |
| Modification Notes | The human forkhead-box (FOX) gene family consists of at least 43 members, including FOXE3, a 288-amino acid protein. FOXE3 is a winged-helix transcription factor that plays a crucial role during the initial stages of lens development and closure of the lens vesicle. FOXE3 may also act as a factor that promotes survival and proliferation while preventing differentiation in the lens epithelium. As the posterior cells of the lens fiber begin to differentiate, expression of FOXE3 is limited to the undifferentiated cells coating the anterior surface of the lens. Congenital primary aphakia (CPA) is a rare developmental disorder caused by a null mutation in the FOXE3 gene that is identified by the absence of a lens. The development of CPA is normally stimulated during the fourth or fifth week of human embryogenesis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of FOXE3 of mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 232-288 mapping at the C-terminus of FOXE3 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 232-288 mapping at the C-terminus of FOXE3 of mouse origin |
| Entrez Gene | 30923 |
|---|
Application
Western blot analysis of FOXE3 expression in non-transfected: (A) and human FOXE3 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of mouse recombinant FOXE3 fusion protein.| Application Notes | recommended for detection of FOXE3 of mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
