| Product Name | F-Spondin Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 508-807 mapping at the C-terminus of F-Spondin of human origin |
| Modification Notes | F-Spondin, also designated Spondin-1 or vascular smooth muscle growth-promoting factor, is a member of the subgroup of the Thrombospondin type 1 class molecules. F-Spondin is a secreted, extracellular matrix-attached protein which patterns axonal trajectories by promoting adhesion and outgrowth of commissural axons, in addition to inhibiting outgrowth of motor axons. F-Spondin contains two conserved domains at the amino terminus, FS1 and FS2, which are regions of homology with Reelin and Mindin. Additionally, F-Spondin contains either six or four thrombospondin repeats (TSRs) at the carboxyl terminus, which are typical of class 2 TSRs. The F-Spondin gene is expressed in the nervous system, mainly at the embryonic floor plate and the hippocampus. F-Spondin may play a role in promoting axonal regeneration after nerve injury and in inflammatory processes in the nervous system. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of F-Spondin and mature Spondin-1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 508-807 mapping at the C-terminus of F-Spondin of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 508-807 mapping at the C-terminus of F-Spondin of human origin |
| Entrez Gene | 10418 |
|---|
| Application Notes | recommended for detection of F-Spondin and mature Spondin-1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
