epitope mapping within an internal region of ZNF295 of human origin
Modification Notes
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF295 (zinc finger protein 295), also known as ZBTB21, is a 1066 amino acid zinc finger protein belonging to the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZNF295 may play a role in transcriptional regulation. Phosphorylated upon DNA damage, ZNF295 contains one BTB (POZ) domain and eight C2H2-type zinc fingers.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of ZNF295 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other ZNF family members also reactive with additional species, including equine, canine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of ZNF295 of human origin
Tissue Specificity
epitope mapping within an internal region of ZNF295 of human origin
Western blot analysis of ZNF295 expression in HEK293 (A) and Jurkat (B) whole cell lysates and HeLa (C), Jurkat (D) and A-431 (E) nuclear extracts.
Application Notes
recommended for detection of ZNF295 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other ZNF family members also reactive with additional species, including equine, canine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.