| Product Name | DNAM-1 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 9-300 mapping at the N-terminus of DNAM-1 of human origin |
| Modification Notes | The T cell antigen receptor (TCR) recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. Additional proteins termed “accessory molecules” are also required for activation and for cytotoxic T lymphocyte (CTL)-mediated cytotoxicity. For instance, CD2, CD4, CD8, LFA-1, and CD28 are examples of well characterized accessory molecules. An accessory molecule designated DNAX accessory molecule-1 or DNAM-1 has been described. DNAM-1 is a transmembrane glycoprotein that is 318 amino acids in length and contains two immunoglobulin-like domains. DNAM-1 is expressed on both T cells and natural killer (NK) cells and participates in primary adhesion during CTL-mediated cytotoxicity. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of DNAM-1 of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 9-300 mapping at the N-terminus of DNAM-1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 9-300 mapping at the N-terminus of DNAM-1 of human origin |
| Entrez Gene | 10666 |
|---|
| Application Notes | recommended for detection of DNAM-1 of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
