MARVELD3 (MARVEL domain-containing protein 3), also known as MRVLDC3 or MARVD3, is a 401 amino acid multi-pass membrane protein that contains one MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain. The MARVEL domain, which is common in Occludin proteins, is a 130 amino acid motif that contains four transmembrane helices, both of which have cytoplasmic N- and C-terminal regions. MARVEL domain-containing proteins are thought to participate in tight junction regulation, the biogenesis of vesicular transport carriers and in cholesterol-rich membrane apposition events. Via its MARVEL domain, MARVELD3 may be involved in developmental and regulatory events throughout the cell. Two isoforms of MARVELD3 exist due to alternative splicing events.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFIHCELISA
recommended for detection of MARVELD3 of mouse, human and canine origin by WB, IP, IF, IHC(P) and ELISA