Application
Western blot analysis of MPPED2 expression in non-transfected: (A) and human MPPED2 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of MPPED2 expression in A204 whole cell lysate.| Product Name | MPPED2 Antibody (L-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against MPPED2 of human origin |
| Modification Notes | MPPED2 (Metallophosphoesterase domain-containing protein 2), also known as C11orf8, FAM1B or 239FB, is a 294 amino acid protein. Expressed primarily in fetal brain tissue, MPPED2 is encoded by a gene that maps to chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double stranded DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of MPPED2 of human and canine origin by WB, IP and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against MPPED2 of human origin |
|---|---|
| Tissue Specificity | raised against MPPED2 of human origin |
| Entrez Gene | 744 |
|---|
Application
Western blot analysis of MPPED2 expression in non-transfected: (A) and human MPPED2 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of MPPED2 expression in A204 whole cell lysate.| Application Notes | recommended for detection of MPPED2 of human and canine origin by WB, IP and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
