Application
Western blot analysis of FAM55D expression in LNCaP (A), Caco-2 (B) and MCF7 (C) whole cell lysates.Application
Western blot analysis of FAM55D expression in Jurkat whole cell lysate.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining.| Product Name | FAM55D Antibody (Z-17) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against FAM55D of human origin |
| Modification Notes | FAM55D (family with sequence similarity 55, member D), also known as C11orf33, is a 544 amino acid secreted protein that is expressed as two isoforms due to alternative splicing events. The gene encoding FAM55D is located on chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and ∫ thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11. The FAM55D gene product has been provisionally designated FAM55D pending further characterization. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of FAM55D of human, rat and canine origin by WB, IP, IF, IHC(P) and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against FAM55D of human origin |
|---|---|
| Tissue Specificity | raised against FAM55D of human origin |
| Entrez Gene | 54827 |
|---|
Application
Western blot analysis of FAM55D expression in LNCaP (A), Caco-2 (B) and MCF7 (C) whole cell lysates.
Application
Western blot analysis of FAM55D expression in Jurkat whole cell lysate.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining.| Application Notes | recommended for detection of FAM55D of human, rat and canine origin by WB, IP, IF, IHC(P) and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
