| Product Name | Deltex-1 Antibody (H-80) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Deltex-1 (DTX) influences B cell lineage and splenic marginal zone B cell commitment. The inhibitory signals mediated through Deltex-1 along with inductive Notch 1 signals act as modulators of T/B lineage commitment. Deltex family members influence Notch signaling and may regulate transcription through interactions with specific transcription factors. Deltex proteins have a basic N-terminus, a central proline-rich region, and a C-terminal RING finger domain, a motif often found in ubiquitin-protein isopeptide ligases (E3). Kurtz (Krz) is an Arrestin family member that binds Deltex in a trimeric complex together with Notch and mediates the degradation of the Notch receptor through a ubiquitination-dependent pathway. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Deltex-1 of mouse, rat and human origin by WB, IP, IF and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 241-320 mapping within an internal region of Deltex-1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 241-320 mapping within an internal region of Deltex-1 of human origin |
| Entrez Gene | 1840 |
|---|
| Application Notes | recommended for detection of Deltex-1 of mouse, rat and human origin by WB, IP, IF and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
