Application
Western blot analysis of PRP4 kinase expression in Jurkat whole cell lysate.| Product Name | PRP4 kinase Antibody (T-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of PRP4 kinase of human origin by WB, IF, IHC(P) and ELISA |
| Modification Notes | The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. PRP4 kinase, also known as PRPF4B, PRP4H or PRP4K, is a 1,007 amino acid nuclear protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Expressed ubiquitously, PRP4 kinase functions to catalyze the ATP-dependent phosphorylation of target proteins and is thought to play a role in pre-mRNA splicing, possibly participating in the spliceosome C complex. Human PRP4 kinase shares 98% sequence identity with its mouse counterpart, suggesting a conserved role between species. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFIHCELISA |
| WB:1:500~1:2000 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of PRP4 kinase of human origin by WB IF IHC(P) and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of PRP4 kinase of human origin by WB, IF, IHC(P) and ELISA |
| Entrez Gene | 8899 |
|---|
Application
Western blot analysis of PRP4 kinase expression in Jurkat whole cell lysate.| Application Notes | WB:1:500~1:2000 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
