Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining of cells in tubules.| Product Name | Perilipin Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-300 mapping at the N-terminus of Perilipin of human origin |
| Modification Notes | The PAT (Perilipin, adipophilin, TIP47) family proteins are evoluntionary related proteins associated with lipid droplets and implicated in intracellular lipid metabolism. The phosphoprotein Perilipin (Peri), also designated lipid droplet-associated protein, belongs to the Perilipin subfamily of proteins. Perilipin localizes on the surface of intracellular lipid droplets within adipocytes, where it protects lipid storage droplets by coating them in adipocytes until they are digested by hormone sensitive lipase (HSL), thereby modulating adipocyte lipid metabolism. As a critical regulator of lipolysis, elevated Perilipin levels have been linked to obesity, as the absence results in leanness. In its phosphorylated state, Perilipin is maximally sensitive to HSL. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of Perilipin of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-300 mapping at the N-terminus of Perilipin of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-300 mapping at the N-terminus of Perilipin of human origin |
| Entrez Gene | 5346 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining of cells in tubules.| Application Notes | recommended for detection of Perilipin of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
