| Product Name | NARG1L Antibody (I-15) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | They cytoplasmic protein NARG1 (NMDA (N-methyl-d-aspartate) receptor-regulated gene 1) interacts with ARD1 or ARD2 to form a complex, which exhibits N-terminal (alpha) acetyltransferase activity. This complex interacts with ribosomal subunits functioning in cotranslational acetylation. During apoptosis, both NARG1 and ARD1 are cleaved by caspases, which results in decreased acetyltransferase activity. Knockdown of NARG1 in HeLa cells leads to apoptosis, indicating that properly functioning NARG1 is essential for cell viability. NARG1 is expressed at high levels in dividing tissues such as bone marrow, testis and embryonal brain and it is overexpressed in papillary thyroid carcinomas. The NARG1-like protein (NARG1L) is an 864 amino acid protein that contains 7 TPR repeats and may also be a component of a complex that displays N-terminal acetyltransferase activity. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of NARG1L of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with all other isoforms also reactive with additional species, including equine, canine, bovine, porcine and avian | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of NARG1L of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of NARG1L of human origin |
| Entrez Gene | 79612 |
|---|
| Application Notes | recommended for detection of NARG1L of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with all other isoforms also reactive with additional species, including equine, canine, bovine, porcine and avian |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
