| Product Name | CDS2 Antibody (P-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | CDS2 (CDP-diglyceride synthetase 2), also known as Phosphatidate cytidylyltransferase 2, is a 445 amino acid enzyme that is localized to the mitochondrial inner membrane. As a multipass-transmembrane protein, CDS2 catalyzes the formation of CDP-diacylgylcerol from phosphaticic acid, which is an important step toward the synthesis of phosphatidylglycerol, phosphatidylinositol and cardiolipin. This is a key regulatory event that determines the amount of phosphatidylinositol 4,5-bisphosphate (PIP2) that is available for signaling. Due to its expression pattern and its role in the phosphoinositide-mediated signaling pathway, the gene encoding CDS2 may be a candidate gene for corneal hereditary endothelial dystrophy 2, a disease characterized by bilateral opacity of the cornea. There are two isoforms of CDS2 which are produced as a result of alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of CDS2 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with isoform CDS2-2 also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of CDS2 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of CDS2 of human origin |
| Entrez Gene | 8760 |
|---|
| Application Notes | recommended for detection of CDS2 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with isoform CDS2-2 also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
