Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF38, also called ZSCAN21, Zipro1 or NY-REN-21, is the human homolog of the mouse Zfp38 protein and is a member of the Krüppel C2H2-type zinc-finger family of transcriptional regulators. Found in proliferating cells, ZNF38 is thought to be associated with gametogenesis in females and with meiosis in males. ZNF38 has a SCAN domain at the N-terminus and exhibits transcriptional activity by forming either a homodimer or a heterodimer with the protein SCAND1.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of ZNF38 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 318-385 mapping within an internal region of ZNF38 of human origin
Tissue Specificity
epitope corresponding to amino acids 318-385 mapping within an internal region of ZNF38 of human origin
Immunofluorescence staining of formalin-fixed Hep G2 cells showing nuclear localization.
Application
Western blot analysis of ZNF38 expression in Hep G2 nuclear extract.
Application Notes
recommended for detection of ZNF38 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.