epitope mapping within an internal region of POLDIP3 of human origin
Modification Notes
POLDIP3 (polymerase delta-interacting protein 3), also known as SKAR or PDIP46, is a 421 amino acid nuclear protein. POLDIP3 interacts with DNA pol ∂ 2, a protein essential to DNA replication, recombination and repair. POLDIP3 is a substrate for the signaling intermediate Rsk-1 and is thought to regulate cell growth. POLDIP3 contains one RRM (RNA recognition motif) domain and is phosphorylated upon DNA damage. POLDIP3 is ubiquitously expressed with highest levels found in heart, kidney, skeletal muscle and brain. Due to alternative splicing, POLDIP3 is expressed as two isoforms.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of POLDIP3 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with family member POLDIP 2 also reactive with additional species, including equine, canine, bovine and avian:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of POLDIP3 of human origin
Tissue Specificity
epitope mapping within an internal region of POLDIP3 of human origin
Western blot analysis of POLDIP3 expression in non-transfected: (A) and mouse POLDIP3 transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of POLDIP3 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with family member POLDIP 2 also reactive with additional species, including equine, canine, bovine and avian:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.