Application
Western blot analysis of TRIM68 expression in DU 145 whole cell lysate.Application
Immuno-peroxidase staining of formalin fixed, paraffin-embedded human kidney showing cytoplasmic staining.| Product Name | TRIM68 Antibody (P-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against TRIM68 of human origin |
| Modification Notes | The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM68 (Tripartite motif-containing protein 68), also known as RNF137 (RING finger protein 137) or SS56, is a 485 amino acid protein that localizes to the perinuclear region of the cytoplasm. Expressed in a variety of tissues with higher expression in prostate, spleen and fetal liver, TRIM68 associates with androgen receptor (AR) and, via this interaction, enhances the transcriptional activity of AR. TRIM68 is found in various cancers, including prostate cancer cells, and is thought to be a therapeutic target for the detection and treatment of prostate cancer. Additionally, TRIM68 is a target of the autoimmune response exhibited in systemic lupus erythematosus (SLE), primary Sjoegren syndrome and HIV-1 infection. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of TRIM68 of human and canine origin by WB, IP, IF, IHC(P) and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against TRIM68 of human origin |
|---|---|
| Tissue Specificity | raised against TRIM68 of human origin |
| Entrez Gene | 55128 |
|---|
Application
Western blot analysis of TRIM68 expression in DU 145 whole cell lysate.
Application
Immuno-peroxidase staining of formalin fixed, paraffin-embedded human kidney showing cytoplasmic staining.| Application Notes | recommended for detection of TRIM68 of human and canine origin by WB, IP, IF, IHC(P) and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
