Application
Western blot analysis of PHF2 expression in non-transfected: (A) and mouse PHF2 transfected: (B) 293T whole cell lysates.| Product Name | PHF2 Antibody (I-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of PHF2 of human origin |
| Modification Notes | PHF2 (PHD finger protein 2), also known as JHDM1E (Jumonji C domain-containing histone demethylase 1E) or GRC5, is a 1,101 amino acid protein belonging to the PHD finger protein family. Members of the PHD finger protein family function as transcriptional regulators that affect gene expression by modulating chromatin structure. Expressed in a wide variety of tissues, PHF2 localizes to the nucleus and contains one PHD-type zinc finger and one JMJC domain, suggesting a possible role for PHF2 in transcription regulation and chromatin remodeling. The gene encoding PHF2 lies in the candidate region for hereditary sensory neuropathy type I (HSN1), a disorder characterized by sensory dysfunction. PHF2 exhists as two isoforms produced by alternative splicing, designated isoform 1 and 2 respectively. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of PHF2 of human origin by WB and IP, ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of PHF2 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of PHF2 of human origin |
| Entrez Gene | 5253 |
|---|
Application
Western blot analysis of PHF2 expression in non-transfected: (A) and mouse PHF2 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of PHF2 of human origin by WB and IP, ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
