In humans, the DMRT genes encode a large family of transcription factors that are related to the Drosophila doublesex proteins. Expressed primarily in the gonads, the DMRT proteins contain cysteine-rich DNA-binding motifs and are thought to play an important role in sexual development. DMRTB1 (Doublesex- and mab-3-related transcription factor B1) is a 342 amino acid protein that contains one DM DNA-binding domain and belongs to the DMRT family. Localized to the nucleus and expressed in the testis, DMRTB1 may participate in developmental processes and, via its DM domain, may bind to DNA and regulate transcription.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
recommended for detection of DMRTB1 of human origin by WB, IP and ELISA: