SLC17A2 (Solute carrier family 17 member 2), also known as NPT3 (Na(+)/PI cotransporter 3), is a 439 amino acid multi-pass membrane protein that belongs to the sodium/anion cotransporter family of the major facilitator superfamily. Expressed in the spleen, small intestine, testis and kidney, SLC17A2 is involved in active transport of phosphate into cells through a sodium/phosphate co-transport system. SLC17A2 contains four transmembrane domains and the gene encoding SLC17A2 localizes to the region of chromosome 6 that is associated with hereditary hemochromatosis (HFE or HH). HFE is a condition characterized by cirrhosis of the liver, hypermelanotic pigmentation of the skin, diabetes and heart failure. Due to alternative splicing events, two SLC17A2 isoforms exist.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFIHCELISA
recommended for detection of SLC17A2 of human origin by WB, IP, IF, IHC(P) and ELISA: