epitope corresponding to amino acids 176-247 mapping at the C-terminus of MOG of human origin
Modification Notes
Myelin oligodendrocyte glycoprotein (MOG) is a myelin component of the central nervous system that influences completion and maintenance of the myelin sheath, cell adhesion and oligodendrocyte microtubule stability. MOG localizes on the oligodendrocyte cell surface and on the outermost lamellae of mature myelin. MOG epitopes targeted by the autoimmune T cell response influence demyelination and contribute to multiple sclerosis (MS). Alternatively spliced transcript variants encoding different isoforms have been identified.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of MOG of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 176-247 mapping at the C-terminus of MOG of human origin
Tissue Specificity
epitope corresponding to amino acids 176-247 mapping at the C-terminus of MOG of human origin
Western blot analysis of MOG expression in 293T whole cell lysate.
Application Notes
recommended for detection of MOG of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.