| Product Name | Myosin Ie Antibody (H-60) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 961-1020 mapping near the C-terminus of Myosin Ie of human origin |
| Modification Notes | Actin is a highly conserved protein that is expressed in all eukaryotic cells. Actin filaments can form both stable and labile structures and are crucial components of microvilli and the contractile apparatus of muscle cells. Trop-onin facilitates interaction between Actin and Myosin by binding to Ca2+. Tro-ponin is made up of at least two subunits, which are divergent in cardiac muscle, fast skeletal muscle and slow skeletal muscle. Myosin is a hexamer of two heavy chains (MHC) and four light chains (MLC) that interacts with Actin to generate the force for diverse cellular movements, including cytokinesis, phagocytosis and muscle contraction. Myosin Ie (MYO1E) is also designated Myosin Ic. Myosin Ie contains 1,109 amino acids. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Myosin Ie of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine: WB:1:100~1:200 IP:1:20~1:100 IF:1:20~1:100 ELISA:1:1000~5000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 961-1020 mapping near the C-terminus of Myosin Ie of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 961-1020 mapping near the C-terminus of Myosin Ie of human origin |
| Entrez Gene | 4643 |
|---|
| Application Notes | recommended for detection of Myosin Ie of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine: WB:1:100~1:200 IP:1:20~1:100 IF:1:20~1:100 ELISA:1:1000~5000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
