| Product Name | Prickle2 Antibody (H-70) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 382-451 mapping within an internal region of Prickle2 of human origin |
| Modification Notes | Prickle2 is an 844 amino acid protein that localizes to the nuclear membrane and contains one PET domain and three LIM zinc-binding domains. Expressed in testis, brain and eye tissue, as well as in gastric and uterine tumors, Prickle2 may be involved in neurite formation during brain growth and may also be associated with tumor formation and metastasis. The gene encoding Prickle2 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Prickle2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 382-451 mapping within an internal region of Prickle2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 382-451 mapping within an internal region of Prickle2 of human origin |
| Entrez Gene | 166336 |
|---|
| Application Notes | recommended for detection of Prickle2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
