epitope corresponding to amino acids 111-170 mapping near the N-terminus of Fcrls of mouse origin
Modification Notes
The Fc receptor homolog (FcRH) family of proteins are related to the classical Fc receptors (FcR) and belong to the immunoglobulin receptor superfamily. The proteins in the FcRH family (namely FcRH1-FcRH6) are type I transmembrane glycoproteins that are involved in immune system regulation and have immunoreceptor-tyrosine inhibitory motifs in their cytoplasmic domains. FcRH proteins are expressed primarily, although not exclusively, by mature B lineage cells, and may also serve important regulatory roles in normal and neoplastic B cell development. Fcrls (Fc receptor-like S), also known as IgSR, Msr2, Fcrh2, IFGP2, MMAN-g, FcRH2sc or moFcRH2sc, is a 509 amino acid mouse protein that is related to the human FcRH family. The mouse ortholog of human FcRH2, Fcrls is expressed in non-lymphoid tissues and may play a role in developmental regulation events throughout the cell.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of Fcrls of mouse and rat origin by WB, IP, IF and ELISA:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 111-170 mapping near the N-terminus of Fcrls of mouse origin
Tissue Specificity
epitope corresponding to amino acids 111-170 mapping near the N-terminus of Fcrls of mouse origin