epitope corresponding to amino acids 1-108 representing full length S-100A15 of mouse origin
Modification Notes
Psoriasin, also known as PSOR1 or S-100A7, is a 101 amino acid protein that belongs to the S-100 family of calcium binding proteins and is secreted via a non-classical secretory pathway into the cytoplasm. Expressed in fetal ear, tongue and skin, Psoriasin is thought to function in the regulation of many cellular processes, including the cell cycle, cell progression and cellular differentiation. Psoriasin contains two EF-hand domains and is highly upregulated in psoriatic epidermis, as well as in bladder squamous cell carcinoma and breast cancer tissue, suggesting a possible role in carcinogenesis. The gene encoding Psoriasin and the related S100A15 gene are thought to have diverged from one mouse gene, designated S100A15. In humans, the S100A15 gene encodes a calcium binding protein, also known as S-100A7A, that shares 95% sequence identity with Psoriasin.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of S-100A15 of mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including bovine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1-108 representing full length S-100A15 of mouse origin
Tissue Specificity
epitope corresponding to amino acids 1-108 representing full length S-100A15 of mouse origin