Application
Western blot analysis of α-defensin 4 expression in THP-1 (A), HT-1080 (B), ZR-75-1 (C) and GA-10 (D) whole cell lysates.| Product Name | α-defensin 4 Antibody (H-51) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 47-97 mapping at the C-terminus of α-Defensin 4 of human origin |
| Modification Notes | Human neutrophil a-defensins (also designated HNPs) are small, cationic, cysteine-rich antimicrobial proteins that play important roles in innate immunity against infectious microbes such as bacteria, fungi and enveloped viruses. a-defensins are synthesized as inactive precursors and are activated by proteolytic cleavage by MMP-7. Paneth cells in small intestinal crypts secrete the a-defensins, which are also termed cryptdins in mice. The cryptdin 4 gene is unique among the Paneth cell a-defensins in that it is inactive in the duodenum, but expressed at maximal levels in the distal small bowel. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of α-Defensin 4 mature chain and precursor of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 47-97 mapping at the C-terminus of &alpha -Defensin 4 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 47-97 mapping at the C-terminus of α-Defensin 4 of human origin |
| Entrez Gene | 1669 |
|---|
Application
Western blot analysis of α-defensin 4 expression in THP-1 (A), HT-1080 (B), ZR-75-1 (C) and GA-10 (D) whole cell lysates.| Application Notes | recommended for detection of α-Defensin 4 mature chain and precursor of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
