| Product Name | Rtn-3 Antibody (H-90) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-90 mapping at the N-terminus of Rtn-3 of human origin |
| Modification Notes | The Reticulon (Rtn) family consists of four members: Rtn-1 (also designated neuroendocrine-specific protein or NSP), Rtn-2 (also designated NSP-like-1), Rtn-3 (also designated NSP-like-2) and Nogo (also designated Rtn-4A). Reticulon proteins are anchored to the membranes of the endoplasmic reticulum through their common C-terminal regions. Localized on human chromosome 14q23.1, the gene encoding Rtn-1 is expressed as three isoforms: Rtn-1A (NSP-A), Rtn-1B (NSP-B) and Rtn-1C (NSP-C). The gene encoding human Rtn-2 is located on chromosome 19q13 and also encodes three isoforms. Rtn-2-A and Rtn-2-C are produced by the use of alternative initiation sites, whereas Rtn-2-B is an alternative splice variant of the Rtn-2-A isoform. Rtn-2-A and Rtn-2-B are highly expressed in brain, while Rtn-2-C is primarily expressed in skeletal muscle. The human Rtn-3 gene is located on chromosome 11q13 and is widely expressed ,with the highest expression being in brain. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Rtn-3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-90 mapping at the N-terminus of Rtn-3 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-90 mapping at the N-terminus of Rtn-3 of human origin |
| Entrez Gene | 10313 |
|---|
| Application Notes | recommended for detection of Rtn-3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
