Application
Western blot analysis of FAM58A/B expression in mouse eye tissue extract.| Product Name | FAM58A/B Antibody (S-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of FAM58A of human origin |
| Modification Notes | FAM58A (family with sequence similarity 58, member A) and FAM58B (family with sequence similarity 58, member B) are 248 amino acid and 252 amino acid proteins, respectively, that belong to the cyclin-like FAM58 subfamily. Existing as multiple alternatively spliced isoforms, FAM58A interacts with Sall1 and is thought to play a role in cellular proliferation. Defects in the gene encoding FAM58A are associated with toe syndactyly, telecanthus, and anogenital and renal malformations (STAR syndrome), which is characterized by renal and anogenital malformations. FAM58B, a protein that is related to FAM58A, is expressed in healthy retina and breast tissue, as well as in retinoblastoma and breast cancer cell lines, suggesting a role for FAM58B in tumor transformation and metastasis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of FAM58A and FAM58B of human origin and FAM58A of mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of FAM58A of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of FAM58A of human origin |
| Entrez Gene | 92002 |
|---|
Application
Western blot analysis of FAM58A/B expression in mouse eye tissue extract.| Application Notes | recommended for detection of FAM58A and FAM58B of human origin and FAM58A of mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
