| Product Name | GLP-2R Antibody (H-57) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 123-179 mapping within an internal region of GLP-2R of human origin |
| Modification Notes | Glucagon, a pancreatic hormone, functions as an antagonist to insulin, stimulating the conversion of glycogen to glucose and increasing blood sugar levels. GLP-1 functions as a transmitter in the central nervous system, inhibiting feeding and drinking behavior. Both Glucagon and GLP-1 function through their specific binding to the Glucagon Receptor or GLP-1R, respectively. The Glucagon Receptor is expressed in liver, kidney and adipose tissue. The GLP-1R expression primarily localizes to areas of the hypothalamus involved in feeding behavior. Both receptors and their ligands serve as potential targets for the therapeutic treatment of diabetes. Glucagon-like peptide 2 receptor, also designated GLP-2 receptor or glp-2r, acts as a receptor for Glucagon-like peptide 2 (GLP-2). GLP-2 is a nutrient-responsive hormone that has various functions in the gastrointestinal tract. The activity of GLP-2R, which is a multi-pass membrane protein, is mediated by G-proteins which activate adenylyl cyclase. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of GLP-2R of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 123-179 mapping within an internal region of GLP-2R of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 123-179 mapping within an internal region of GLP-2R of human origin |
| Entrez Gene | 9340 |
|---|
| Application Notes | recommended for detection of GLP-2R of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
