| Product Name | Exportin 6 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-300 mapping at the N-terminus of Exportin 6 of human origin |
| Modification Notes | Exportins, which recruit cargo to the nucleoplasm, preferentially bind their substrates at high RanGTP concentrations in the nucleus and exit the nucleus as trimeric cargo-Exportin-RanGTP complexes. These complexes are then disassembled via the hydrolysis of GTP. Exportin 6, also known as RANBP20 or XPO6, is a 1,125 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one importin N-terminal domain. Existing in a complex with Profilin-1 and ∫-Actin, Exportin 6 functions to mediate the nuclear export of Actin-associated protein structures in somatic cells. The gene encoding Exportin 6 maps to human chromosome 16, which houses over 900 genes and comprises nearly 3% of the human genome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Exportin 6 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-300 mapping at the N-terminus of Exportin 6 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-300 mapping at the N-terminus of Exportin 6 of human origin |
| Entrez Gene | 23214 |
|---|
| Application Notes | recommended for detection of Exportin 6 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
