| Product Name | α-taxilin Antibody (M-74) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 481-554 mapping at the C-terminus of α-taxilin of mouse origin |
| Modification Notes | å-taxilin is a novel binding partner of the syntaxin family which is implicated in intracellular vesicle trafficking. Through its C-terminal coiled-coil region, å-taxilin interacts with the nascent polypeptide-associated complex (NAC), which acts as a transcriptional coactivator. Although å-taxilin binds to both the å and ∫ NAC subunits, the main interaction is through åNAC. Co-expression of å-taxilin with overexpressed åNAC eliminates the nuclear distribution of åNAC, originally distributed throughout the cytosol and nucleus. ∫- and ©-taxilins, additional members of the taxilin family, bind to åNAC and affect its nuclear distribution, suggesting that the taxilin family is involved not only in the translational process through its interaction with NAC but also in the transcriptional process through its interaction with åNAC alone. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of α-taxilin of mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 481-554 mapping at the C-terminus of &alpha -taxilin of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 481-554 mapping at the C-terminus of α-taxilin of mouse origin |
| Entrez Gene | 109658 |
|---|
| Application Notes | recommended for detection of α-taxilin of mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
