Application
Western blot analysis of IFIT3 expression in Caki-1 (A) and COLO 320DM (B) whole cell lysates.Application
Western blot analysis of IFIT3 expression in Hep G2 whole cell lysate.Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney tissue showing nuclear and cytoplasmic localization.Application
Western blot analysis of IFIT3 expression in HeLa whole cell lysate.| Product Name | IFIT3 Antibody (E-22) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The tetratricopeptide repeat (TPR) motif is a degenerate, 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways. At the sequence level, there can be up to 16 tandem TPR repeats, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity. IFIT3 (interferon-induced protein with tetratricopeptide repeats 3), also known as IRG2, IFI60, IFIT4, ISG60 or RIG-G, is a 490 amino acid protein that contains eight TPR repeats and may play a role in cell cycle regulation and cellular proliferation. The gene encoding IFIT3 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of IFIT3 of human origin by WB IP IF IHC(P) and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of IFIT3 of human origin by WB, IP, IF, IHC(P) and ELISA |
| Entrez Gene | 3437 |
|---|
Application
Western blot analysis of IFIT3 expression in Caki-1 (A) and COLO 320DM (B) whole cell lysates.
Application
Western blot analysis of IFIT3 expression in Hep G2 whole cell lysate.
Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney tissue showing nuclear and cytoplasmic localization.
Application
Western blot analysis of IFIT3 expression in HeLa whole cell lysate.| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
