epitope mapping within an internal region of FAM58A of human origin
Modification Notes
LOC727895 is a 194 amino acid protein that is encoded by a gene which maps to chromosome 13. Comprising nearly 4% of human DNA, chromosome 13 contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. The LOC727895 gene product has been provisionally designated LOC727895 pending further characterization.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of FAM58A and FAM58B of human origin and FAM58A of mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of FAM58A of human origin
Tissue Specificity
epitope mapping within an internal region of FAM58A of human origin
Western blot analysis of LOC727895 expression in mouse eye tissue extract.
Application Notes
recommended for detection of FAM58A and FAM58B of human origin and FAM58A of mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.