Application
Western blot analysis of CL-P1 expression in Jurkat whole cell lysate.| Product Name | CL-P1 Antibody (A-22) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of CL-P1 of human origin by WB, IP and ELISA |
| Modification Notes | CL-P1 (collectin placenta protein 1), also known as COLEC12 (collectin sub-family member 12), NSR2, SRCL or SCARA4, is a 742 amino acid single-pass type II membrane protein that contains one C-type lectin domain and three collagen-like domains. Expressed in kidney, brain, thymus and colon, as well as in perivascular macrophages, CL-P1 is a scavenger receptor that exhibits a variety of functions related with host defense, including promoting the binding and phagocytosis of Gram-positive and Gram-negative bacteria. Additionally, CL-P1 mediates the recognition and degradation of damaged or apoptotic cells and can bind to carbohydrate antigens, thereby facilitating their removal from the host. CL-P1 is thought to play a role in the clearance of ∫-Amyloid plaques from the neural tissue of people affected with Alzheimer’s disease (AD), suggesting that CL-P1 may be involved in reducing the progression of AD. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of CL-P1 of human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of CL-P1 of human origin by WB, IP and ELISA |
| Entrez Gene | 81035 |
|---|
Application
Western blot analysis of CL-P1 expression in Jurkat whole cell lysate.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
