Application
Western blot analysis of HSPC117 expression in non-transfected: (A) and human HSPC117 transfected: (B) 293T whole cell lysates.| Product Name | HSPC117/FAAP Antibody (S-15) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | HSPC117, also known as C22orf28, is a 505 amino acid protein that is encoded by a gene which maps to human chromosome 22. A highly homologous protein identified in rodents, FAAP (focal adhesion associated protein), encoded by murine D10Wsu52e gene, has been suggested to play a role in regulating cell adhesion dynamics. Chromosome 22 houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of HSPC117 of human origin and FAAP of mouse and rat origin by WB, IP, IF and ELISA non cross-reactive with HSPC016, HSPC038, and HSPC300 also reactive with additional species, including equine, canine, bovine, porcine and avian | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of HSPC117 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of HSPC117 of human origin |
| Entrez Gene | 51493 |
|---|
Application
Western blot analysis of HSPC117 expression in non-transfected: (A) and human HSPC117 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of HSPC117 of human origin and FAAP of mouse and rat origin by WB, IP, IF and ELISA non cross-reactive with HSPC016, HSPC038, and HSPC300 also reactive with additional species, including equine, canine, bovine, porcine and avian |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
