| Product Name | PATZ1 Antibody (P-17) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. PATZ1 (POZ (BTB) and AT hook containing zinc finger 1), also known as PATZ, RIAZ, ZBTB19, ZNF278 or ZSG, is a 687 amino acid protein that localizes to the nucleus and contains one A.T hook DNA-binding domain, one BTB (POZ) domain and seven C2H2-type zinc fingers. Expressed ubiquitously, PATZ1 functions as a transcriptional repressor and may be involved in the pathogenesis of small round cell sarcoma, as well as human colorectal cancer. Multiple isoforms of PATZ1 exist due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of PATZ1 of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of PATZ1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of PATZ1 of human origin |
| Entrez Gene | 23598 |
|---|
| Application Notes | recommended for detection of PATZ1 of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
