| Product Name | BNPI Antibody (H-55) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The BNPI (brain specific Na(+)-dependent inorganic phosphate(Pi) cotransporter) gene, also designated VGLUT1 (vesicular glutamate transporter), is located on chromosome 19q13 and encodes a 560 amino acid protein with 6-8 transmembrane-spanning domains (1,2). BNPI is expressed predominantly in neurons of the cerebral cortex, hippocampus, and cerebellum, and is more highly expressed in adult brain compared to fetal brain (1,2). BNPI localizes almost exclusively to nerve terminals forming asymmetric excitatory-type synapses and associates preferentially with the membranes of small synaptic vesicles (3). In the plasma membrane, BNP1 imports phospate ions, which are required for glutmatergic neurotransmission (4,5). Expression of BNPI results in glutamate uptake by intracellular vesicles, which defines a glutamatergic phenotype in neurons (5,6). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of BNPI of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-55 mapping at the N-terminus of BNPI of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-55 mapping at the N-terminus of BNPI of human origin |
| Entrez Gene | 57030 |
|---|
| Application Notes | recommended for detection of BNPI of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
