Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining of cells in tubules.Application
Western blot analysis of LHR expression in mouse testis (A) and rat testis (B) tissue extracts.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining of cells in glomeruli and tubuli at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.Application
Western blot analysis of LHR expression in mouse testis tissue extract.| Product Name | LHR Antibody (H-50) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 28-77 mapping within an extracellular domain of LHR of human origin |
| Modification Notes | Lutropin (also designated luteinizing hormone) plays a role in spermatogenesis and ovulation by stimulating the testis and ovaries to produce steroids (1). Gonadotropin (also designated choriogonadotropin) production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy (2). Ovaries and testis abundantly express luteinizing hormone/choriogonadotropin receptor (LHR) as a seven transmembrane, G protein-coupled receptor glycoprotein (3,4). LHR influences the protective effect of pregnancy and gonadotropin against breast cancer (5). The expression of LHR on breast carcinoma correlates in part to the degree of tumor differentiation (5). LHR-positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women (5). The gene encoding human LHR maps to chromosome 2p21 (6). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of LHR of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 28-77 mapping within an extracellular domain of LHR of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 28-77 mapping within an extracellular domain of LHR of human origin |
| Entrez Gene | 3973 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining of cells in tubules.
Application
Western blot analysis of LHR expression in mouse testis (A) and rat testis (B) tissue extracts.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining of cells in glomeruli and tubuli at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
Application
Western blot analysis of LHR expression in mouse testis tissue extract.| Application Notes | recommended for detection of LHR of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
