| Product Name | SHBG Antibody (M-207) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 197-403 mapping at the C-terminus of SHBG of mouse origin |
| Modification Notes | Sex hormone-binding globulin (SHBG) precursor is a secreted homodimer that binds steroid hormones. SHBG, also known as testis-specific androgen-binding protein or testosterone-estradiol binding globulin (TeBG), functions as an androgen transport protein and is involved in receptor mediated processes. It is specific for 7-b-estradiol and 5-a-dihydrotestosterone and testosterone. By controlling the plasma concentration of steroid hormones, SHBG regulates the plasma metabolic clearance rate of the hormones. Isoforms 1 and 2 of the protein are detected in liver and testis. In testis SHBG is synthesized by the Sertoli cells, secreted into the seminiferous tubule and then transported to the epididymis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SHBG of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 197-403 mapping at the C-terminus of SHBG of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 197-403 mapping at the C-terminus of SHBG of mouse origin |
| Entrez Gene | 6462 |
|---|
| Application Notes | recommended for detection of SHBG of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
