Application
Western blot analysis of ANG I expression in Hep G2 whole cell lysate.Application
Western blot analysis of ANG I expression in non-transfected: (A) and human ANG I transfected: (B) CHO whole cell lysates.Application
Western blot analysis of human recombinant ANG I.| Product Name | ANG I Antibody (H-123) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 25-147 of ANG I of human origin |
| Modification Notes | Angiogenesis is defined as the process of neovascularization and formation of new blood vessels from the established micro-circulation. Angiogenin (ANG or ANG I) is a non-glycosylated polypeptide, 123 amino acids in length, whose function is central to this process. ANG I shows a high degree of homology with known ribonucleases such as pancreatic ribonuclease A, and the capacity of ANG I to induce blood vessel growth is critically dependent on its ribonucleolytic activity. ANG I is thought to be involved in the development of solid tumors, and ANG I antagonists are capable of inhibiting tumor growth. By a poorly understood mechanism, ANG I is endocytosed by subconfluent endothelial cells and translocated to the nucleus where it accumulates in the nucleolus. The ANG I receptor has not yet been identified. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of precursor and mature ANG I of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 25-147 of ANG I of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 25-147 of ANG I of human origin |
| Entrez Gene | 283 |
|---|
Application
Western blot analysis of ANG I expression in Hep G2 whole cell lysate.
Application
Western blot analysis of ANG I expression in non-transfected: (A) and human ANG I transfected: (B) CHO whole cell lysates.
Application
Western blot analysis of human recombinant ANG I.| Application Notes | recommended for detection of precursor and mature ANG I of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
