Application
Western blot analysis of HoxB9 expression in Hep G2 whole cell lysate.Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human lung tissue showing nuclear localization.Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human heart tissue showing nuclear localization.| Product Name | HoxB9 Antibody (A-21) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. The mammalian HOX gene complex consists of 39 genes that are located on 4 linkage groups, which are dispersed over 4 chromosomes. HOX genes that occupy the same relative position along the 5’ to 3’ coordinate (trans-paralogous genes) are more similar in sequence and expression pattern than adjacent HOX genes on the same chromosome. In mice, the HoxB cluster contains HoxB1 to HoxB9 and HoxB13, which are transcribed in the same direction. HoxB9 associates with the transcriptional cofactors BTG1 and BTG2, which enhance HoxB9 transcription. Alterations in HoxB9 expression, as with other Hox family member, has been implicated in leukemia. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB,IP,IF,IHC,ELISA |
| Species Reactivity | Human,Mouse,Rat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of HoxB9 of human origin by WB IP IF IHC(P) and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of HoxB9 of human origin by WB, IP, IF, IHC(P) and ELISA |
| Entrez Gene | 3219 |
|---|
Application
Western blot analysis of HoxB9 expression in Hep G2 whole cell lysate.
Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human lung tissue showing nuclear localization.
Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human heart tissue showing nuclear localization.| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
